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CASPASE 1
Descriptors Found:
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DeCS
Descriptor
English
:
Caspase 1
Descriptor
Spanish
:
Caspasa 1
Descriptor
Portuguese
:
Caspase 1
Synonyms
English
:
CASP1 Caspase
Caspase, CASP1
Convertase, IL-1 beta
Converting Enzyme, Interleukin-1
Converting Enzyme, Interleukin-1beta
ICE Protease
IL 1 beta Convertase
IL 1 beta Converting Enzyme
IL-1 beta Convertase
IL-1 beta-Converting Enzyme
IL1BC Enzyme
Interleukin 1 Converting Enzyme
Interleukin 1beta Converting Enzyme
Interleukin-1 Converting Enzyme
Interleukin-1beta Converting Enzyme
Pro Caspase 1
Pro-Caspase-1
Procaspase 1
Procaspase-1
beta Convertase, IL-1
beta-Converting Enzyme, IL-1
Tree Number:
D08.811.277.656.262.500.126.550.100
D08.811.277.656.300.200.126.550.100
D12.644.360.075.405.550.100
D12.776.476.075.405.550.100
Definition
English
:
A long pro-domain caspase that has specificity for the precursor form of
INTERLEUKIN-1BETA
. It plays a role in
INFLAMMATION
by catalytically converting the inactive forms of
CYTOKINES
such as
interleukin-1beta
to their active, secreted form.
Caspase 1
is referred as
interleukin-1beta
converting enzyme and is frequently abbreviated ICE.
Entry Combination - descr/qualif
English
:
Caspase 1
/
antagonists & inhibitors
use
Caspase Inhibitors
See Related
English
:
Apoptosis
Interleukin-1
History Note
English
:
99; use CASPASE 1 (NM) 1989-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33827
Unique Identifier:
D020170
Occurrence in VHL
:
Similar:
DeCS